Tag: innovation

  • Cyprus Forum Brussels: Vision for Digitalisation and Competitiveness in EU Presidency

    Cyprus Forum Brussels: Vision for Digitalisation and Competitiveness in EU Presidency

    digitalisation — The Cyprus Forum Brussels has set a clear vision for digitalisation and competitiveness as Cyprus prepares to take on the rotating Council Presidency of the European Union.

    Digitalisation: Steering the EU Digital Agenda

    During the event, a high-level panel discussed how Cyprus intends to influence the EU’s digital strategy, particularly through significant legislative initiatives such as the Digital Omnibus, the Business Wallet, and cybersecurity reforms. Cyprus aims to create a coherent and investment-friendly digital environment that enhances European competitiveness.

    Key Panel Participants

    Key figures in the discussion included Giorgos Ioannides, Deputy Permanent Representative of Cyprus to the EU; Despina Spanou, Deputy Director-General for Networks & Technology at the European Commission; Tzvetoslav Mitev, Director for Data Economy & Public Administration; and Antoine Mathieu Collin, Visiting Fellow at Bruegel. The session was moderated by Eddy Wax from Euractiv.

    Presidency Philosophy and Principles

    Giorgos Ioannides articulated the overarching philosophy of the Cyprus Presidency, emphasising that digital transition is essential for enhancing competitiveness, resilience, and European sovereignty. He stated that rather than introducing new regulations, Cyprus aims to serve as a “guardian of balance,” ensuring that negotiations around digital files remain coherent and streamlined.

    Ioannides highlighted three guiding principles for the upcoming presidency:

    • Proportionality
    • Avoidance of regulatory overlaps and inconsistencies
    • Predictable rules that attract investment

    He stressed the importance of agility in the EU’s approach, especially as companies operate in a competitive global market. He suggested that strategic public procurement could act as a catalyst for innovation and enhance the EU’s technological capabilities.

    Understanding the Digital Omnibus

    The Digital Omnibus package is a significant initiative from the European Commission aimed at simplifying the EU’s digital regulatory framework. Despina Spanou clarified that the focus of the Omnibus is on simplification without lowering existing standards. She reiterated that the General Data Protection Regulation (GDPR) remains a global reference standard, and the emphasis is on clarifying obligations rather than diluting rights.

    The Omnibus is designed to provide a consistent regulatory framework, reducing administrative burdens on businesses, especially small and medium-sized enterprises (SMEs). It aims to replace fragmented obligations with clearer, more predictable rules that align with cornerstone laws such as the GDPR, Digital Services Act, and Digital Markets Act.

    Cybersecurity Reforms

    During the forum, Spanou also touched on upcoming cybersecurity initiatives. A unified cyber-incident notification mechanism, referred to as ‘report once, reach many’, is set to replace the current fragmented reporting system under GDPR and other frameworks.

    The review of the Cybersecurity Act will focus on clarifying the mandate of ENISA and streamlining certification schemes, thereby addressing supply-chain security gaps more effectively. Spanou emphasised that while simplification is essential, it will not come at the expense of maintaining robust cybersecurity standards.

    Business Wallet: A Tool for Competitiveness

    Both Spanou and Tzvetoslav Mitev highlighted the Business Wallet as a crucial element for enhancing Europe’s digital economy. Described as “an eID for businesses,” the Business Wallet will allow companies to authenticate themselves securely and conduct administrative or financial procedures without the need for paperwork or physical presence.

    Mitev pointed out that for the Business Wallet to achieve its intended impact, public administrations must adopt and integrate it into their core procedures. He warned that a purely voluntary approach could lead to low uptake, a concern that has affected previous eID initiatives.

    Caution on Regulatory Simplification

    Antoine Mathieu Collin provided a cautionary perspective on the implications of regulatory simplification. He argued that while easing compliance requirements could foster innovation, it might also disproportionately benefit major platforms that already dominate the digital landscape. Without appropriate safeguards, such simplification could exacerbate the competitive disadvantages faced by smaller European firms.

    Collin highlighted the EU’s challenge of finding a balance between fostering innovation through simplification while preventing excessive concentration of digital power in the hands of a few large players.

    Looking Ahead: Making Existing Rules Work

    Across the panel, a consistent theme emerged: the Cyprus EU Presidency aims to be evaluated not by the number of new initiatives launched but by the effectiveness of implementing existing rules. The priorities include cutting overlaps, simplifying compliance, and ensuring that cybersecurity regulations remain robust yet workable.

    As Cyprus prepares to assume the presidency, the choices made in the coming months will significantly impact Europe’s digital competitiveness for the next decade. Ensuring that the simplification efforts empower small and mid-sized firms remains a critical challenge for the EU.

  • Cyprus Defence Ministry to Finalise National Plan for EU Safe Funding

    Cyprus Defence Ministry to Finalise National Plan for EU Safe Funding

    eu safe — eu safe — The Cyprus defence ministry will convene the defence industry council in the coming days to finalise the national action plan for the European Union’s Safe financial instrument. Defence capability development and armament director Panayiotis Hadjipavlis confirmed the meeting’s details during an interview with the Cyprus News Agency (CNA).

    Eu safe: Extraordinary Meeting Scheduled

    Chaired by Defence Minister Vassilis Palmas, the council will hold an extraordinary meeting to assess the ministry’s progress and establish final recommendations. These recommendations are crucial for the plan’s submission to the European Commission, which is due by November 30.

    Preparations Underway Since June

    Hadjipavlis explained that the ministry has been diligently preparing the Safe investment plan since June, with the intention of incorporating Cypriot defence and technology companies wherever feasible. The council comprises various stakeholders, including the presidents of the Cyprus Chamber of Commerce and Industry (Keve), the Employers and Industrialists Federation (Oev), and the Cyprus Defence Industry Association.

    Strengthening International Cooperation

    The defence ministry is actively participating in and co-organising events with foreign partners to enhance collaboration between Cypriot and international defence companies. Upcoming activities will involve the UK Ministry of Defence, as well as the embassies of France and Poland, focusing on joint research, technology development, and procurement strategies.

    Recent European Defence Agency Visit

    A team from the European Defence Agency (EDA) visited Cyprus on October 23-24 to explore new opportunities for cooperation with EU member states. During this visit, the EDA’s executive director met with Minister Palmas. Hadjipavlis remarked that relations between Cyprus and the agency are “excellent,” highlighting Cyprus as one of the agency’s staunchest supporters within the EU framework.

    Innovative Defence Research Initiatives

    As part of ongoing research and innovation efforts, a demonstration showcasing two completed projects under the Athena defence research programme is scheduled for November 10 at a National Guard base. These projects include an anti-drone system and a situational awareness platform designed to assist battlefield decision-making. Furthermore, two new programmes, Athena 2 and Athena Plus, are being prepared for launch in 2026 to expand upon these initiatives.

    Growing Defence Sector Landscape

    Currently, around 30 Cypriot companies are engaged in the defence sector, with a rising interest from firms specialising in dual-use technologies. Hadjipavlis noted that several Cypriot companies have already joined European Defence Fund consortia, positioning Cyprus seventh in Europe for successful funding applications.

    Upcoming Defence Events and Collaborations

    Several significant defence events are on the horizon, including a conference focused on technological advancements in the sector, taking place on November 11-12, under the auspices of the defence ministry. Additionally, the ministry will participate in a joint event organised by Keve and the French Embassy, in collaboration with the deputy ministry of research, aimed at promoting modern technologies and dual-use products.

    Future Conferences and Initiatives

    In early 2025, a bilateral conference will be co-organised with the UK Ministry of Defence and the Cyprus High Commission in London, aimed at fostering partnerships between defence industry associations from both nations. Another event with the Polish Embassy in Nicosia will concentrate on cybersecurity and cyber defence collaboration.

    Comprehensive Development Toolkit in Progress

    The ministry is also engaged in discussions with European experts to develop a comprehensive toolkit for the Cypriot defence industry. This includes formulating a national defence industry strategy, a detailed action plan, and necessary updates to legislation and the national defence industry registry.

    Significant EU Funding Secured

    Cyprus has successfully secured €500,000 in EU funding to advance this development package following a competitive selection process. Hadjipavlis pointed out that Cyprus stands out as one of the few EU countries to receive such support, contrasting with many others that rely on national budgets for similar initiatives.

  • Thalassemia — Cyprus Institute Launches Innovative Gene Therapy Project for Thalassemia

    Thalassemia — Cyprus Institute Launches Innovative Gene Therapy Project for Thalassemia

    A new gene therapy project at the Cyprus Institute of Neurology and Genetics aims to tackle the root cause of beta-thalassemia, a prevalent inherited blood disorder in Cyprus.

    • A new gene therapy project at the Cyprus Institute of Neurology and Genetics aims to tackle the root cause of beta-thalassemia, a prevalent inherited blood disorder in Cyprus.
    • As the project progresses, the potential impact on the lives of those affected by beta-thalassemia could be transformative, moving towards a future where the disease is no longer a lifelong burden.

    Addressing a Critical Health Challenge

    The Molecular Genetics Thalassaemia Department (MGTD) has unveiled the BETA-BET: Targeted Base Editing for Beta Thalassemia project, designed to develop a one-time, curative therapy. This initiative specifically targets the HBBIVSI-110 mutation, the most common cause of beta-thalassemia on the island.

    Understanding Beta-Thalassemia

    Beta-thalassemia is a serious hereditary condition resulting from mutations in the β-globin gene (HBB), which plays a vital role in producing haemoglobin, the protein responsible for oxygen transport in the blood. Individuals affected by this disorder often require lifelong blood transfusions to manage chronic anaemia and compensate for their body’s inadequate production of functional red blood cells.

    Project Timeline and Funding

    The BETA-BET project commenced on June 1, 2025, and is set to last for 24 months. It has a total funding of €198.83 million, with financial support from the Research and Innovation Foundation (RIF), the European Union, and the Republic of Cyprus.

    Building on Previous Success

    This new project builds on a prior RIF-funded initiative that involved collaboration with George Papanikolaou Hospital, the Aristotle University of Thessaloniki, and the University of Freiburg. That earlier study successfully evaluated gene-editing tools in stem cells from individuals with two copies of the HBBIVSI-110 mutation, demonstrating the potential to correct genetic defects and restore normal red blood cell production.

    Scientific Goals of the BETA-BET Project

    The BETA-BET project has outlined two primary scientific objectives. The first goal is to expand and validate the effectiveness of “base editing” technology for a broader patient demographic known as compound heterozygotes. These patients carry the HBBIVSI-110 mutation alongside another mutation in the same gene, representing a significant portion of the thalassemia population. In fact, globally, compound heterozygotes are over three times more common than homozygotes, making this research particularly relevant in regions such as Greece and Egypt, where the HBBIVSI-110 mutation is prevalent in over 19 per cent of the population.

    Innovative Gene Editing Technology

    Base editing acts like a microscopic “biological pencil and eraser,” allowing scientists to precisely identify and correct a single “letter” error in the DNA sequence without cutting the DNA strands. This method provides a safer and more controlled approach to gene therapy compared to traditional techniques, paving the way for broader clinical application.

    New Delivery Methods for Gene Therapy

    The second objective involves the development of a cutting-edge delivery platform using engineered virus-like particles (eVLPs). These particles function as “microscopic delivery drones,” designed to transport gene-editing tools directly to blood-producing stem cells. This innovative delivery method could ultimately simplify the treatment process, allowing it to be administered via a simple injection rather than the current complex and costly procedure that requires the removal, editing, and reinfusion of stem cells.

    Collaboration and Expertise

    The project is being coordinated by Dr Petros Patsali, Associate Scientist at MGTD, alongside a team that includes Dr Carsten W. Lederer, Head of Department, Dr Nikoletta Papaioannou, Postdoctoral Researcher, and Dr Panayiota Papasavva, Hematologist and Clinician-Researcher. They are collaborating with a network of national and international partners, including Dr Soteroula Christou from the State Health Services Organization’s Thalassaemia Clinic in Cyprus, Prof Dr Toni Cathomen from the University Medical Center Freiburg in Germany, Dr Annarita Miccio from the Imagine Institute of Genetic Diseases in France, and Dr Maria N. Dimopoulou from Laiko General Hospital in Athens.

    A Promising Future for Thalassemia Patients

    The Cyprus Institute of Neurology and Genetics has stated, “The BETA-BET programme represents a crucial step toward a potential cure for the majority of people living with thalassemia.” By broadening the therapy’s reach and developing a safer delivery system, the institute believes this research could offer a personalised, one-time treatment for many patients who currently depend on lifelong transfusions.

    As the project progresses, the potential impact on the lives of those affected by beta-thalassemia could be transformative, moving towards a future where the disease is no longer a lifelong burden.